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Supplement Reviews
Octopamine
This is a unique and interesting compound that we looked at several
years ago. It is actually one of the components of Zhi Shi, which is
a Chinese herb that comes from the immature dried fruit of Citrus
aurantium commonly referred to as bitter orange. When harvested
early in its ripening, Zhi shi is composed of a number of chemical
amines including: synephrine, octopamine, hordenine, N-Methyltyramine
and Tyramine. A study published in January 2000 concluded that "octopamine
could be considered as an endogenous selective beta 3 adrenergic
agonist." This could mean it has great potential for fat loss in
humans even though the beta 3 receptor seems to be a newer and more
unclear area of research. This specific receptor is more potent in
animals but may have a function in humans. In fact, this is one of
the ways ephedrine helps to burn fat effectively—agonizing beta
receptors which leads to great fat burning, heat production, and
increased metabolic rate. Some scientists think that the beta 3
receptor is the most powerful and has the greatest fat burning,
muscle sparing effects when stimulated. Only further research will
tell if this ingredient is the “real deal”.
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